Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) Is Characterized by a...
Background/Purpose: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is characterized by abrupt onset of obsessive-compulsive disorder (OCD) and/or food restriction with other specified...
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Ongoing Disease Activity in Juvenile Idiopathic Arthritis (JIA) 18 Years...
Background/Purpose: Previously, we showed that ILAR JIA categories defined at disease onset change considerably during the first 8 years of disease course. Whether achieved remission and defined ILAR...
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Juvenile Spondyloarthritis in the Childhood Arthritis and Rheumatology...
Background/Purpose: To describe characteristics of children with enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) enrolled in the Childhood Arthritis and Rheumatology Research...
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Defining the Prevalence of Depression and Anxiety Symptoms in Adolescents...
Background/Purpose: We aimed to evaluate the prevalence of depressive and/or anxiety symptoms in adolescents with juvenile idiopathic arthritis (JIA) and explore the association with demographic and...
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Protracted Febrile Myalgia Findings on Magnetic Resonance Imaging
Background/Purpose: Protracted febrile myalgia syndrome (PFMS) is a rare complication of familial Mediterranean fever (FMF) which consist of prolonged attack of fever, excruciating myalgia (up to 6...
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Pseudotumor Cerebri Syndrome in Children with Systemic Lupus Erythematosus
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease that typically affects multiple organs and can lead to potentially fatal complications. Management of...
View ArticleChallenges Faced by Families of Children with an Auto-inflammatory Disease
Background/Purpose: Auto-inflammatory diseases (AIDs) are rare disorders that usually present in young children. Disease episodes, characterized by recurrent inflammation, are often frequent and...
View ArticleResolution of Coronary Artery Changes in Patients with Refractory Kawasaki...
Background/Purpose: Treatment for patients with Kawasaki Disease (KD) refractory to standard therapy is controversial. Most experts recommend a second dose of IVIG [1], and for IVIG-resistant cases,...
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Clinical Features and Outcomes in Chronic Atypical Neutrophilic Dermatosis...
Background/Purpose: Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature (CANDLE) Syndrome is an autoinflammatory interferonopathy caused by mutations in the genes...
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Chronic Non-bacterial Osteomyelitis (CNO): Correlation Between Clinical and...
Background/Purpose: Due to the lack of widely accepted diagnostic criteria or disease biomarkers, chronic non-bacterial osteomyelitis (CNO) remains a diagnosis of exclusion. Whole-body MRI (WB-MRI) has...
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Anti-Citrullinated Protein Antibodies (ACPA) and Bony Erosions in...
Background/Purpose: Despite being a well-established biomarker for classification of aggressive bony disease in adults with RA, ACPA have not yet been described in the ILAR criteria for polyarticular...
View ArticleReproductive Health Concerns in Young Adults with Pediatric Onset Rheumatic...
Background/Purpose: While patients and families of those with pediatric onset rheumatic diseases have keen interest and unaddressed worry about the impact of their rheumatic disease on their current...
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Evaluation of B-cell Depletion with Rituximab and IVIG Concurrent Treatment...
Background/Purpose: Rituximab is standard therapy in treating autoimmune brain disease (ABD) including refractory autoimmune encephalitis (AE) and Neuromyelitis Optica Spectrum Disease (NMOSD)....
View ArticleA Pilot Randomized Controlled Trial of the iCanCope Pain Self-management...
Background/Purpose: Pain is the most common symptom of Juvenile Idiopathic Arthritis (JIA), a chronic childhood illness that has potentially debilitating effects on health-related quality of life...
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Risk Score of Macrophage Activation Syndrome in Patients with Systemic...
Background/Purpose: Macrophage Activation Syndrome (MAS) is a severe, life-threatening, complication of rheumatic diseases in childhood, particularly of systemic Juvenile Idiopathic Arthritis (sJIA),...
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Prosthetic Temporomandibular Joint Replacement in a Cohort of Adolescent...
Background/Purpose: Temporomandibular joint (TMJ) arthritis is present in 40-96% of children with Juvenile Idiopathic Arthritis (JIA) (1). TMJ arthritis can be difficult to identify, treat, and can...
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Levels of Anxiety and Depressive Symptoms in Juvenile Idiopathic Arthritis...
Background/Purpose: Children with chronic diseases have higher rates of mental health issues and less favorable outcomes than the general pediatric population. Children with JIA experience pain and...
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Parental Adverse Childhood Experience (ACE) Exposure Is Predictive of Active...
Background/Purpose: Adverse Childhood Experiences (ACEs) have been recognized for more than two decades as risk factors for poor health outcomes in adults. Nevertheless, the impact of patient exposure...
View ArticleMyD88 S209R-Mediated Immune Dysregulation in Mouse Models of Arthritis
Background/Purpose: MYD88 is a critical adaptor protein that connects Toll-like and IL-1 receptor signaling to activation of NF-kB. We previously reported a heterozygous de novo mutation in MYD88...
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