Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) Is Characterized by a...
Background/Purpose: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is characterized by abrupt onset of obsessive-compulsive disorder (OCD) and/or food restriction with other specified...
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Ongoing Disease Activity in Juvenile Idiopathic Arthritis (JIA) 18 Years...
Background/Purpose: Previously, we showed that ILAR JIA categories defined at disease onset change considerably during the first 8 years of disease course. Whether achieved remission and defined ILAR...
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Juvenile Spondyloarthritis in the Childhood Arthritis and Rheumatology...
Background/Purpose: To describe characteristics of children with enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) enrolled in the Childhood Arthritis and Rheumatology Research...
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Defining the Prevalence of Depression and Anxiety Symptoms in Adolescents...
Background/Purpose: We aimed to evaluate the prevalence of depressive and/or anxiety symptoms in adolescents with juvenile idiopathic arthritis (JIA) and explore the association with demographic and...
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Protracted Febrile Myalgia Findings on Magnetic Resonance Imaging
Background/Purpose: Protracted febrile myalgia syndrome (PFMS) is a rare complication of familial Mediterranean fever (FMF) which consist of prolonged attack of fever, excruciating myalgia (up to 6...
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Pseudotumor Cerebri Syndrome in Children with Systemic Lupus Erythematosus
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease that typically affects multiple organs and can lead to potentially fatal complications. Management of...
View ArticleChallenges Faced by Families of Children with an Auto-inflammatory Disease
Background/Purpose: Auto-inflammatory diseases (AIDs) are rare disorders that usually present in young children. Disease episodes, characterized by recurrent inflammation, are often frequent and...
View ArticleResolution of Coronary Artery Changes in Patients with Refractory Kawasaki...
Background/Purpose: Treatment for patients with Kawasaki Disease (KD) refractory to standard therapy is controversial. Most experts recommend a second dose of IVIG [1], and for IVIG-resistant cases,...
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Clinical Features and Outcomes in Chronic Atypical Neutrophilic Dermatosis...
Background/Purpose: Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature (CANDLE) Syndrome is an autoinflammatory interferonopathy caused by mutations in the genes...
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Chronic Non-bacterial Osteomyelitis (CNO): Correlation Between Clinical and...
Background/Purpose: Due to the lack of widely accepted diagnostic criteria or disease biomarkers, chronic non-bacterial osteomyelitis (CNO) remains a diagnosis of exclusion. Whole-body MRI (WB-MRI) has...
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The Killer Immunoglobulin-like Receptor KIR3DL1 in Combination with HLA-Bw4...
Background/Purpose: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is characterized by abrupt onset of obsessive-compulsive disorder (OCD) and/or food restriction with other specified...
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Evaluation of Self-report Screening Measures in the Detection of Depressive...
Background/Purpose: Screening for co-morbid psychiatric disorder is of high clinical importance in childhood-onset systemic lupus erythematosus (cSLE). However, there are no validated screening...
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Long-Term Outcomes in Children Born to Anti-Ro and/or anti-La Positive Mothers
Background/Purpose: Neonatal Lupus Erythematosus (NLE) is an acquired autoimmune disorder associated with the transplacental passage of maternal anti-Ro and/or anti-La antibodies. NLE manifestations...
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Implications of Positive Tests for ANCA in a Pediatric Population
Background/Purpose: Testing for ANCA, particularly performed by ELISA (anti-MPO/PR3) is highly sensitive and specific for ANCA-associated vasculitis (AAV). However ANCA testing may be used in clinical...
View ArticleAdvanced Multidisciplinary Care: A New Approach to Childhood Arthritis
Background/Purpose: Many patients are overwhelmed with the diagnosis of chronic childhood arthritis and require long-term treatments. Our objective was to develop a new, child and family centered,...
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The Importance of the Patient Global Health Assessment of Disease Activity in...
Background/Purpose: Polyarticular juvenile idiopathic arthritis (pJIA) is a subtype of JIA wherein more than four joints are affected with arthritis; it is characterized by unpredictable flares and...
View ArticleClinical and Laboratory Characteristics in Juvenile-onset Systemic Lupus...
Background/Purpose: Systemic lupus erythematous (SLE) is a systemic autoimmune/inflammatory condition. Up to 20% of patients develop symptoms before their 18th birthday and are diagnosed with...
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Change in Treatments and Outcomes After Implementation of a National...
Background/Purpose: Juvenile idiopathic arthritis (JIA) is currently the most common childhood chronic rheumatic disease with high burden and socioeconomic costs for the patient’s family and the health...
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Association of Plasma Metabolomic Profiles with Methotrexate Response in...
Background/Purpose: Despite efforts to identify biomarkers to guide therapy in the treatment of juvenile idiopathic arthritis (JIA), drug therapy remains a trial-and-error process. In the case of...
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Increasing Rates of Standardized Depression Screening in Youth with Systemic...
Background/Purpose: Depression is common among youth with SLE. Early identification and treatment of depression has the potential to improve health outcomes for youth with SLE. Pediatric...
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